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Jay Sennett, a light-skinned mature-aged trans man, standing indoors and smiling slightly. He is bald, with a wrinkled face and grey eyebrows. He is wearing a black sweater.

Long-Term Effects of Testosterone

Talking Head
2019
United States of America
Jay Sennett, an American trans man who started taking testosterone in 1996, shares his experiences and offers some advice in this short video.

Watch.


Available Summary:

"I began taking testosterone in 1996. In this video I discuss long-term consequences of taking testosterone for me. Please note this video is educational only. You should discuss taking testosterone with a qualified physician or nurse practitioner. Living long-term on testosterone, I've gone bald. That's about the worst thing that has happened to me. But I can't say I'm surprised. My father and younger brother are also bald." -YouTube.


Jack's Summary:

In this video, an American female-to-male transsexual who began transitioning in 1986 speaks about the long-term effects of being on testosterone, in his experience. He describes himself as being very happy with the changes, happy to be ageing as a man, loving having a deeper voice, and being empowered to have sex with women. He says that, while he has experienced high cholesterol and borderline high blood pressure, both have been controlled through exercise and, where needed, medication (a common situation for many older men, and many people in testosterone-dominant bodies regardless of gender). He says that he cannot point to any negatives solely due to testosterone. He urges people considering starting hormone replacement therapy, specifically testosterone, to consult a doctor and/or a nurse practitioner. He recommends caution when it comes to highly politicised and negative online conversations about long-term testosterone use.

Entry last updated:

24 Feb 2026

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Thank you so much to the trans men and gender-diverse people who have reached out with recommendations. Now that my health is better, I am working on the site again. Thank you for your patience!

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